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Patricia A MacDonald Selected Research

Febuxostat

12/2017Effects of Febuxostat in Early Gout: A Randomized, Double-Blind, Placebo-Controlled Study.
11/2013Randomized controlled trial of febuxostat versus allopurinol or placebo in individuals with higher urinary uric acid excretion and calcium stones.
1/2013Preservation of renal function during gout treatment with febuxostat: a quantitative study.
3/2012The efficacy and safety of febuxostat for urate lowering in gout patients ≥65 years of age.
2/2012African American patients with gout: efficacy and safety of febuxostat vs allopurinol.
2/2012Women with gout: efficacy and safety of urate-lowering with febuxostat and allopurinol.
12/2011Treating hyperuricemia of gout: safety and efficacy of febuxostat and allopurinol in older versus younger subjects.
7/2011Febuxostat in gout: serum urate response in uric acid overproducers and underexcretors.
6/2009Clinical efficacy and safety of successful longterm urate lowering with febuxostat or allopurinol in subjects with gout.
12/2005Febuxostat compared with allopurinol in patients with hyperuricemia and gout.
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Patricia A MacDonald Research Topics

Disease

17Gout
12/2017 - 03/2005
5Hyperuricemia
12/2017 - 03/2005
2Pain (Aches)
07/2011 - 07/2011
1Breast Neoplasms (Breast Cancer)
01/2019
1Neoplasms (Cancer)
01/2019
1Synovitis
12/2017

Drug/Important Bio-Agent (IBA)

16Uric Acid (Urate)IBA
12/2017 - 03/2005
11FebuxostatFDA Link
12/2017 - 03/2005
6Allopurinol (Remid)FDA LinkGeneric
03/2012 - 12/2005
2Xanthine OxidaseIBA
12/2005 - 03/2005
2ColchicineFDA LinkGeneric
12/2005 - 03/2005
1CateninsIBA
01/2019
1Glycoproteins (Glycoprotein)IBA
01/2019
1Xanthine DehydrogenaseIBA
11/2013
1Indicators and Reagents (Reagents)IBA
07/2011
1Biomarkers (Surrogate Marker)IBA
07/2011
1ametantrone (HAQ)IBA
07/2011
1Naproxen (Naprosyn)FDA LinkGeneric
12/2005
1Pharmaceutical PreparationsIBA
12/2005

Therapy/Procedure

7Therapeutics
12/2017 - 06/2008